By coincidence rather than by design, the Swiss chemist Albert Hofmann makes a sensational discovery in the spring of 1943. He realizes that he is dealing with a powerful molecule that will have an impact that reaches far beyond the scientific world. THE SUBSTANCE is an investigation into our troubled relationship with LSD, told from its beginnings to today.

By coincidence rather than by design, the Swiss chemist Albert Hofmann makes a sensational discovery in the spring of 1943. He realizes that he is dealing with a powerful molecule that will have an impact that reaches far beyond the scientific world. THE SUBSTANCE is an investigation into our troubled relationship with LSD, told from its beginnings to today.